African research wants to develop its ethical dimension

Agil Katumanyane, a doctoral student in entomology, observes infected insects under a microscope at the University of Pretoria, South Africa, November 18, 2021. LINDOKUHLE SOBEKWA / MAGNUM PHOTOS POUR «LE MONDE» History has accelerated… The fact that the 8 billion humans are currently confronted with the same epidemic questions their common destiny and puts the … Read more

Researchers develop ultra-thin ‘laptop on the bone’

Journal Reference: Le Cai, Alex Burton, David A. Gonzales, Kevin Albert Kasper, Amirhossein Azami, Roberto Peralta, Megan Johnson, Jakob A. Bakall, Efren Barron Villalobos, Ethan C. Ross, John A. Szivek, David S. Margolis, Philipp Gutruf. Osseosurface electronicsthin, wireless, battery-free and multimodal musculoskeletal biointerfaces. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-27003-2 “As a surgeon, I am … Read more

Scientists develop promising vaccine method against recurrent UTI

Journal Reference: Michael A. Luzuriaga, Fabian C. Herbert, Olivia R. Brohlin, Jashkaran Gadhvi, Thomas Howlett, Arezoo Shahrivarkevishahi, Yalini H. Wijesundara, Sundharamani Venkitapathi, Kavya Veera, Ryanne Ehrman, Candace E. Benjamin, Sarah Popal, Michael D. Burton, Molly A. Ingersoll, Nicole J. De Nisco, Jeremiah J. Gassensmith. Metal–Organic Framework Encapsulated Whole-Cell Vaccines Enhance Humoral Immunity against Bacterial Infection. … Read more

Researchers develop rapid computer software to track pandemics as they happen

Journal Reference: Daniel Novikov, Sergey Knyazev, Mark Grinshpon, Pelin Icer, Pavel Skums, Alex Zelikovsky. Scalable Reconstruction of SARS-CoV-2 Phylogeny with Recurrent Mutations. Journal of Computational Biology, 2021; 28 (11): 1130 DOI: 10.1089/cmb.2021.0306 The group of computer science and mathematics researchers says its new software is several orders of magnitude faster than existing computer programs and … Read more

As we develop, the brain connects lessons learned differently

Journal Reference: Margaret L. Schlichting, Katharine F. Guarino, Hannah E. Roome, Alison R. Preston. Developmental differences in memory reactivation relate to encoding and inference in the human brain. Nature Human Behaviour, 2021; DOI: 10.1038/s41562-021-01206-5 The researchers found that whereas adults build integrated memories with inferences already baked in, children and adolescents create separate memories that … Read more

Engineers develop process that turns ordinary clothing into biosensors

Journal Reference: Taehwan Lim, Huanan Zhang, Sohee Lee. Gold and silver nanocomposite-based biostable and biocompatible electronic textile for wearable electromyographic biosensors. APL Materials, 2021; 9 (9): 091113 DOI: 10.1063/5.0058617 Chemical engineering assistant professor Huanan Zhang has developed a process that turns clothing fabric into biosensors which measure a muscle’s electrical activity as it is worn. … Read more

Scientists develop direct-acting antiviral to treat COVID-19

Journal Reference: Adi Idris, Alicia Davis, Aroon Supramaniam, Dhruba Acharya, Gabrielle Kelly, Yaman Tayyar, Nic West, Ping Zhang, Christopher L.D. McMillan, Citradewi Soemardy, Roslyn Ray, Denis O’Meally, Tristan A. Scott, Nigel A.J. McMillan, Kevin V. Morris. A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19. Molecular Therapy, 2021; DOI: 10.1016/j.ymthe.2021.05.004 Traditional antivirals reduce symptoms and help people … Read more

Researchers develop CRISPR-based rapid diagnostic tool for SARS-CoV-2

Journal Reference: Daniel J. Brogan, Duverney Chaverra-Rodriguez, Calvin P. Lin, Andrea L. Smidler, Ting Yang, Lenissa M. Alcantara, Igor Antoshechkin, Junru Liu, Robyn R. Raban, Pedro Belda-Ferre, Rob Knight, Elizabeth A. Komives, Omar S. Akbari. Development of a Rapid and Sensitive CasRx-Based Diagnostic Assay for SARS-CoV-2. ACS Sensors, 2021; DOI: 10.1021/acssensors.1c01088 The new SENSR (sensitive … Read more

Researchers develop proof-of-concept treatment that elevates adult and fetal hemoglobin

Journal Reference: Silvia Pires Lourenco, Danuta Jarocha, Valentina Ghiaccio, Amaliris Guerra, Osheiza Abdulmalik, Ping La, Alexandra Zezulin, Kim Smith-Whitley, Janet L. Kwiatkowski, Virginia Guzikowski, Yukio Nakamura, Tobias Raabe, Laura Breda, Stefano Rivella. Inclusion of a shRNA targeting BCL11A into a β-globin expressing vector allows concurrent synthesis of curative adult and fetal hemoglobin. Haematologica, 2021; DOI: … Read more

Researchers develop ‘dimmer swap’ to help control gene therapy

Journal Reference: Alex Mas Monteys, Amiel A. Hundley, Paul T. Ranum, Luis Tecedor, Amy Muehlmatt, Euyn Lim, Dmitriy Lukashev, Rajeev Sivasankaran, Beverly L. Davidson. Regulated control of gene therapies by drug-induced splicing. Nature, 2021; DOI: 10.1038/s41586-021-03770-2 “We’re taking the field of gene therapy to an entirely new level where fine-tuned dosing is required for safety, … Read more